SREBF1 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	EP300	ENSGGOP00000005899	ENSGGOP00000008032	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	MED15	ENSGGOP00000005899	ENSGGOP00000021420	CREB binding protein.	Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.429
CREBBP	SREBF1	ENSGGOP00000005899	ENSGGOP00000050798	CREB binding protein.	Sterol regulatory element binding transcription factor 1.	0.881
ENSGGOP00000045173	SCAP	ENSGGOP00000045173	ENSGGOP00000037185	Uncharacterized protein.	SSD domain-containing protein.	0.898
ENSGGOP00000045173	SREBF1	ENSGGOP00000045173	ENSGGOP00000050798	Uncharacterized protein.	Sterol regulatory element binding transcription factor 1.	0.926
EP300	CREBBP	ENSGGOP00000008032	ENSGGOP00000005899	E1A binding protein p300.	CREB binding protein.	0.999
EP300	MED15	ENSGGOP00000008032	ENSGGOP00000021420	E1A binding protein p300.	Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.451
EP300	SREBF1	ENSGGOP00000008032	ENSGGOP00000050798	E1A binding protein p300.	Sterol regulatory element binding transcription factor 1.	0.925
FBXW7	SREBF1	ENSGGOP00000026487	ENSGGOP00000050798	F-box and WD repeat domain containing 7.	Sterol regulatory element binding transcription factor 1.	0.941
LPIN1	LPIN2	ENSGGOP00000035295	ENSGGOP00000000325	Lipin 1.	Lipin 2.	0.978
LPIN1	LPIN3	ENSGGOP00000035295	ENSGGOP00000051493	Lipin 1.	Lipin 3.	0.994
LPIN1	SREBF1	ENSGGOP00000035295	ENSGGOP00000050798	Lipin 1.	Sterol regulatory element binding transcription factor 1.	0.946
LPIN2	LPIN1	ENSGGOP00000000325	ENSGGOP00000035295	Lipin 2.	Lipin 1.	0.978
LPIN2	LPIN3	ENSGGOP00000000325	ENSGGOP00000051493	Lipin 2.	Lipin 3.	0.996
LPIN2	SREBF1	ENSGGOP00000000325	ENSGGOP00000050798	Lipin 2.	Sterol regulatory element binding transcription factor 1.	0.922
LPIN3	LPIN1	ENSGGOP00000051493	ENSGGOP00000035295	Lipin 3.	Lipin 1.	0.994
LPIN3	LPIN2	ENSGGOP00000051493	ENSGGOP00000000325	Lipin 3.	Lipin 2.	0.996
LPIN3	SREBF1	ENSGGOP00000051493	ENSGGOP00000050798	Lipin 3.	Sterol regulatory element binding transcription factor 1.	0.922
MED15	CREBBP	ENSGGOP00000021420	ENSGGOP00000005899	Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	CREB binding protein.	0.429
MED15	EP300	ENSGGOP00000021420	ENSGGOP00000008032	Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	E1A binding protein p300.	0.451