SNX12 protein (Gorilla gorilla) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gorilla gorilla

NCBI taxonomy Id: 9593
Other names: G. gorilla, Troglodytes gorilla, gorilla, western gorilla

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFTR	ENSGGOP00000037430	ENSGGOP00000021557	ENSGGOP00000037430	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Sorting nexin 3.	0.644
CFTR	SNX12	ENSGGOP00000021557	ENSGGOP00000052299	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Sorting nexin 12.	0.642
ENSGGOP00000037430	CFTR	ENSGGOP00000037430	ENSGGOP00000021557	Sorting nexin 3.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.644
ENSGGOP00000037430	RAB7A	ENSGGOP00000037430	ENSGGOP00000005440	Sorting nexin 3.	RAB7A, member RAS oncogene family.	0.918
ENSGGOP00000037430	SLC11A2	ENSGGOP00000037430	ENSGGOP00000008772	Sorting nexin 3.	Solute carrier family 11 member 2.	0.741
ENSGGOP00000037430	SNX12	ENSGGOP00000037430	ENSGGOP00000052299	Sorting nexin 3.	Sorting nexin 12.	0.998
ENSGGOP00000037430	SNX5	ENSGGOP00000037430	ENSGGOP00000008759	Sorting nexin 3.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.846
ENSGGOP00000037430	VPS26A	ENSGGOP00000037430	ENSGGOP00000010180	Sorting nexin 3.	Uncharacterized protein.	0.996
ENSGGOP00000037430	VPS26B	ENSGGOP00000037430	ENSGGOP00000006655	Sorting nexin 3.	VPS26, retromer complex component B.	0.990
ENSGGOP00000037430	VPS29	ENSGGOP00000037430	ENSGGOP00000037435	Sorting nexin 3.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.974
ENSGGOP00000037430	VPS35	ENSGGOP00000037430	ENSGGOP00000008594	Sorting nexin 3.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.996
ENSGGOP00000037430	WLS	ENSGGOP00000037430	ENSGGOP00000032688	Sorting nexin 3.	Wnt ligand secretion mediator.	0.861
RAB7A	ENSGGOP00000037430	ENSGGOP00000005440	ENSGGOP00000037430	RAB7A, member RAS oncogene family.	Sorting nexin 3.	0.918
RAB7A	SNX12	ENSGGOP00000005440	ENSGGOP00000052299	RAB7A, member RAS oncogene family.	Sorting nexin 12.	0.762
RAB7A	SNX5	ENSGGOP00000005440	ENSGGOP00000008759	RAB7A, member RAS oncogene family.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.760
RAB7A	VPS26A	ENSGGOP00000005440	ENSGGOP00000010180	RAB7A, member RAS oncogene family.	Uncharacterized protein.	0.913
RAB7A	VPS26B	ENSGGOP00000005440	ENSGGOP00000006655	RAB7A, member RAS oncogene family.	VPS26, retromer complex component B.	0.820
RAB7A	VPS29	ENSGGOP00000005440	ENSGGOP00000037435	RAB7A, member RAS oncogene family.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.927
RAB7A	VPS35	ENSGGOP00000005440	ENSGGOP00000008594	RAB7A, member RAS oncogene family.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.916
SLC11A2	ENSGGOP00000037430	ENSGGOP00000008772	ENSGGOP00000037430	Solute carrier family 11 member 2.	Sorting nexin 3.	0.741