STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEFA4Defensin alpha 4. (97 aa)    
Predicted Functional Partners:
CEACAM8
Carcinoembryonic antigen related cell adhesion molecule 8.
   
  
 0.987
LOC100970329
Peptidase S1 domain-containing protein.
   
 0.986
CTSG
Cathepsin G; Belongs to the peptidase S1 family.
   
 0.904
BPI
Bactericidal permeability increasing protein.
   
  
 0.873
MPO
Myeloperoxidase.
   
  
 0.845
MS4A3
Membrane spanning 4-domains A3.
   
  
 0.829
AZU1
Azurocidin 1.
   
 
 0.827
LSR
Lipolysis stimulated lipoprotein receptor.
      
 0.825
CAMP
Cathelicidin antimicrobial peptide.
   
  
 0.815
MMP8
Matrix metallopeptidase 8.
   
  
 0.792
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.