Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
DOHHDeoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family. (289 aa)    
Predicted Functional Partners:
DHPS
Uncharacterized protein.
   
 0.998
EIF5A2
Eukaryotic translation initiation factor 5A.
  
 0.965
ENSPPAP00000037003
Eukaryotic translation initiation factor 5A.
  
 0.955
EIF5A
Eukaryotic translation initiation factor 5A.
  
 0.938
ENSPPAP00000035735
Eukaryotic translation initiation factor 5A.
  
 0.938
PES1
Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family.
   
    0.789
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
  
 
  0.770
ZNF593
Zinc finger protein 593.
   
  
 0.766
FH
Fumarate hydratase.
     
 0.761
CD163L1
CD163 molecule like 1.
    
   0.746
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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