STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF286AUncharacterized protein. (479 aa)    
Predicted Functional Partners:
CC2D1A
Uncharacterized protein.
      
 0.786
BBX
BBX high mobility group box domain containing.
    
 
 0.643
MEF2D
Myocyte enhancer factor 2D.
    
 
 0.597
OLIG3
Oligodendrocyte transcription factor 3.
    
 
 0.533
PDGFC
Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family.
      
 0.533
SPRY1
Sprouty RTK signaling antagonist 1.
    
 
 0.515
HDAC9
Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
   
 0.471
FOXG1
Uncharacterized protein.
    
 0.448
SLC6A1
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.422
NFIC
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
    
 
 0.400
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.