Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)    
Predicted Functional Partners:
USP30
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
    
 
 0.841
DNAJC13
DnaJ heat shock protein family (Hsp40) member C13.
      
 0.817
FBXO21
F-box protein 21.
     
 0.797
PTP4A1
Protein tyrosine phosphatase 4A1.
      
 0.790
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
     
 0.783
SSH1
Slingshot protein phosphatase 1.
    
 
 0.782
FGF1
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
     
  0.782
FGF3
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
  0.782
FGF5
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.779
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1.
     
 0.743
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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