STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA1Pleckstrin homology domain containing A1. (404 aa)    
Predicted Functional Partners:
RINT1
RAD50 interactor 1.
    
 0.691
USE1
Unconventional SNARE in the ER 1.
    
 0.680
NBAS
Neuroblastoma amplified sequence.
   
 0.636
ZW10
Zw10 kinetochore protein.
    
 0.623
ENSPPAP00000009997
Syntaxin-18_N domain-containing protein.
   
 0.581
STX18
Syntaxin 18.
   
 0.581
SEC22A
SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family.
   
 0.567
SEC22C
SEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family.
   
 0.567
NSF
N-ethylmaleimide sensitive factor, vesicle fusing ATPase.
    
 0.477
COPB2
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
    
 0.424
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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