Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSDL2Hydroxysteroid dehydrogenase like 2. (419 aa)    
Predicted Functional Partners:
ECI2
Enoyl-CoA delta isomerase 2.
  
 0.952
HADH
Uncharacterized protein.
  
 0.892
CAT
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
   
 0.887
ADHFE1
Fe-ADH domain-containing protein.
  
 0.872
CRYL1
Crystallin lambda 1.
  
 0.863
PEX5
Peroxisomal biogenesis factor 5.
   
 0.838
SUGCT
Succinyl-CoA:glutarate-CoA transferase.
  
 0.838
AMACR
Alpha-methylacyl-CoA racemase.
  
 0.838
ACOX2
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.835
ACOX1
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.835
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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