STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GOSR2Uncharacterized protein. (256 aa)    
Predicted Functional Partners:
STX5
Syntaxin 5; Belongs to the syntaxin family.
   
 0.999
BET1
Bet1 golgi vesicular membrane trafficking protein.
   
 0.999
GOSR1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
   
 0.992
SCFD1
Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family.
    
 0.990
BET1L
Bet1 golgi vesicular membrane trafficking protein like.
   
 0.989
YKT6
YKT6 v-SNARE homolog; Belongs to the synaptobrevin family.
   
 0.965
SEC22A
SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family.
    
 0.955
SEC22C
SEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family.
    
 0.951
USO1
USO1 vesicle transport factor.
    
 0.944
CAPZA1
F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
     
 0.891
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.