Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
XDHXanthine dehydrogenase. (1272 aa)    
Predicted Functional Partners:
BTN1A1
Butyrophilin subfamily 1 member A1.
   
 
 0.971
PNP
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
   
 
 0.970
GDA
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
 
 0.969
CYP1A2
Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family.
   
 
 0.926
TPMT
Thiopurine S-methyltransferase.
     
 0.922
HPRT1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.922
NAT2
Arylamine N-acetyltransferase 2; Belongs to the arylamine N-acetyltransferase family.
   
 
 0.921
NAT1
N-acetyltransferase 1; Belongs to the arylamine N-acetyltransferase family.
   
 
 0.916
APRT
Adenine phosphoribosyltransferase.
     
 0.914
LACC1
Uncharacterized protein.
     
  0.900
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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