Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SDHAF1Succinate dehydrogenase complex assembly factor 1; Belongs to the complex I LYR family. (115 aa)    
Predicted Functional Partners:
SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
    
 0.978
SDHAF3
Succinate dehydrogenase complex assembly factor 3.
    
 0.950
NFKBID
ANK_REP_REGION domain-containing protein.
      
 0.925
OVOL3
Uncharacterized protein.
      
 0.906
ENSPPAP00000006541
Uncharacterized protein.
    
 0.897
SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
    
 0.897
PRODH2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
      
 0.890
HLCS
Holocarboxylase synthetase.
      
 0.861
DMPK
DM1 protein kinase.
      
 0.757
SDHAF4
Succinate dehydrogenase complex assembly factor 4.
     
 0.747
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.