STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFECBHLH domain-containing protein. (437 aa)    
Predicted Functional Partners:
FBXW5
F-box and WD repeat domain containing 5.
      
 0.869
TRIOBP
TRIO and F-actin binding protein.
      
 0.709
CTSK
Cathepsin K; Belongs to the peptidase C1 family.
   
  
 0.571
OSR2
Odd-skipped related transciption factor 2.
    
 0.537
TFE3
Transcription factor binding to IGHM enhancer 3.
    
 
0.516
TYR
Tyrosinase.
    
 0.468
MITF
Melanocyte inducing transcription factor.
    
 
0.464
HOXA10
Homeobox A10.
      
 0.459
DCT
Dopachrome tautomerase.
    
 0.425
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.