Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KPNA4Importin subunit alpha; Functions in nuclear protein import. (521 aa)    
Predicted Functional Partners:
KPNA3
Importin subunit alpha; Functions in nuclear protein import.
  
0.997
RCC1
Regulator of chromosome condensation 1.
   
 
 0.989
KPNB1
Karyopherin subunit beta 1.
   
 0.985
RELA
RELA proto-oncogene, NF-kB subunit.
   
 0.973
NFKB1
Nuclear factor kappa B subunit 1.
    
 0.972
CSE1L
Chromosome segregation 1 like.
   
 0.962
KPNA1
Importin subunit alpha; Functions in nuclear protein import.
  
0.950
PRPF19
Pre-mRNA processing factor 19.
   
   0.823
RANBP3
RAN binding protein 3.
   
 
 0.761
CTDSPL2
CTD small phosphatase like 2.
   
 
 0.755
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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