STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPPAP00000001242BHLH domain-containing protein. (117 aa)    
Predicted Functional Partners:
TCF3
Transcription factor 3.
    
 
 0.867
TCF4
Transcription factor 4.
    
 
 0.845
TCF12
Transcription factor 12.
    
 
 0.727
NKX2-5
NK2 homeobox 5.
    
 
 0.585
MYOG
Myogenin.
    
 
 0.523
CDK2
Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.
    
 
 0.502
GATA4
GATA binding protein 4.
   
 
 0.494
IL7R
Interleukin 7 receptor.
      
 0.487
SPI1
Spi-1 proto-oncogene.
    
 
 0.483
ZBTB18
Zinc finger and BTB domain containing 18.
    
 
 0.482
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.