Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
SPINK8Serine peptidase inhibitor, Kazal type 8 (putative). (97 aa)    
Predicted Functional Partners:
REG4
Regenerating family member 4.
      
 0.888
PNOC
Prepronociceptin.
      
 0.871
CAMSAP2
Calmodulin regulated spectrin associated protein family member 2.
      
 0.622
USP43
Ubiquitin specific peptidase 43; Belongs to the peptidase C19 family.
      
 0.555
MTMR14
Myotubularin related protein 14.
      
 0.486
VWC2
Von Willebrand factor C domain containing 2.
      
 0.486
ADAMTS14
ADAM metallopeptidase with thrombospondin type 1 motif 14.
      
 0.418
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2.
      
 0.418
WDR7
WD repeat domain 7.
      
 0.415
BPIFA1
BPI fold containing family A member 1.
      
 0.411
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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