Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IFNA17Interferon alpha 17. (189 aa)    
Predicted Functional Partners:
IFNAR1
Interferon alpha and beta receptor subunit 1.
    
 0.946
IFNAR2
Uncharacterized protein.
    
 0.846
IRF7
Interferon regulatory factor 7.
    
 0.773
TYK2
Tyrosine-protein kinase.
    
 0.756
JAK1
Tyrosine-protein kinase.
    
 0.752
IFNGR1
Interferon gamma receptor 1.
  
  
 0.744
IRF3
Interferon regulatory factor 3.
    
 0.740
JAK2
Tyrosine-protein kinase.
    
 0.738
IL10RB
Interleukin 10 receptor subunit beta.
    
 0.736
IL12RB1
Interleukin 12 receptor subunit beta 1.
  
  
 0.732
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.