Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)    
Predicted Functional Partners:
NCKAP1
NCK associated protein 1.
    
 0.999
WASF1
WASP family member 1.
    
 0.998
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.998
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.998
NCKAP1L
NCK associated protein 1 like.
    
 0.996
ABI1
Abl interactor 1.
    
 0.994
WASF3
WASP family member 3.
    
 0.988
ABI2
Abl interactor 2.
    
 0.979
ENSPPAP00000024258
WH2 domain-containing protein.
    
 0.976
WASF2
WASP family member 2.
    
 0.976
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.