Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DPP6Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family. (803 aa)    
Predicted Functional Partners:
KCND2
Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family.
   
 
 0.865
ITPR2
Inositol 1,4,5-trisphosphate receptor type 2.
      
 0.815
PRNP
Major prion protein; Belongs to the prion family.
    
 
 0.765
DPP10
Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family.
   
 
 0.753
LGI1
Leucine rich glioma inactivated 1.
   
  
 0.753
NFASC
Neurofascin.
   
  
 0.704
CNTNAP2
Contactin associated protein like 2.
   
  
 0.696
KCND3
Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family.
   
 
 0.692
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
   
  
 0.675
SYP
Synaptophysin.
   
  
 0.648
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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