STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HLA-CMajor histocompatibility complex, class I, C; Belongs to the MHC class I family. (397 aa)    
Predicted Functional Partners:
B2M
Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
   
 0.998
TAPBP
TAP binding protein.
   
 0.975
LOC100987319
Uncharacterized protein.
    
 0.966
CALR
Calreticulin.
    
 0.963
PDIA3
Protein disulfide-isomerase.
    
 0.949
CD8B
Ig-like domain-containing protein.
    
 0.947
KIR3DL3
Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3.
    
 0.882
KLRD1
Killer cell lectin like receptor D1.
    
 0.875
HLA-E
Major histocompatibility complex, class I, E; Belongs to the MHC class I family.
  
0.867
CD8A
CD8a molecule.
   
 0.831
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.