Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CALRCalreticulin. (417 aa)    
Predicted Functional Partners:
PDIA3
Protein disulfide-isomerase.
   
 0.999
TAPBP
TAP binding protein.
    
 0.997
ENSPPAP00000031464
Thioredoxin domain-containing protein.
   
 0.994
P4HB
Protein disulfide-isomerase.
   
 0.989
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.989
ENSPPAP00000025633
Uncharacterized protein.
   
 0.986
CANX
Calnexin.
   
 0.985
TAP1
Transporter 1, ATP binding cassette subfamily B member.
   
 0.978
LOC100977183
Uncharacterized protein.
   
 0.978
PDIA4
Protein disulfide-isomerase A4.
   
 0.971
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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