Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DUSP13Dual specificity phosphatase 13; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (334 aa)    
Predicted Functional Partners:
LMNA
Lamin A/C; Belongs to the intermediate filament family.
   
 
 0.775
VRK3
VRK serine/threonine kinase 3.
    
 0.625
SMIM12
Small integral membrane protein 12.
   
   0.607
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 
 0.593
TPPP
Tubulin polymerization promoting protein.
   
  
 0.551
KRT36
Keratin 36; Belongs to the intermediate filament family.
    
 
 0.541
AP3M1
AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family.
   
  
 0.533
AP3M2
AP-3 complex subunit mu-2.
   
  
 0.533
LYZL4
Lysozyme like 4; Belongs to the glycosyl hydrolase 22 family.
      
 0.527
LOC100970534
Uncharacterized protein.
   
 
 0.518
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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