Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ACTL7AActin like 7A; Belongs to the actin family. (435 aa)    
Predicted Functional Partners:
RIT2
Ras like without CAAX 2.
    
 0.930
CTNNAL1
Uncharacterized protein.
    
 0.865
ELP1
Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.
    
 
 0.846
BAG4
BCL2 associated athanogene 4.
      
 0.782
DNAH17
Dynein axonemal heavy chain 17.
   
 0.755
TES
Testin LIM domain protein.
    
 
 0.753
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 0.688
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
      
 0.645
ARPC2
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.631
ENAH
WH1 domain-containing protein.
   
 0.603
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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