STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLE5TLE family member 5, transcriptional modulator. (264 aa)    
Predicted Functional Partners:
TLE4
TLE family member 4, transcriptional corepressor.
    
0.872
TLE3
TLE family member 3, transcriptional corepressor.
    
0.850
TLE1
TLE family member 1, transcriptional corepressor.
    
0.831
NDFIP2
Nedd4 family interacting protein 2.
      
 0.765
RIPPLY1
Ripply transcriptional repressor 1.
    
 
 0.736
VENTX
VENT homeobox.
    
 
 0.724
PTRH2
Peptidyl-tRNA hydrolase 2.
    
 
 0.687
RIPPLY2
Ripply transcriptional repressor 2.
    
 
 0.685
F2RL1
F2R like trypsin receptor 1.
      
 0.678
TLE6
TLE family member 6, subcortical maternal complex member.
 
  
 0.631
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.