Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CHTF8Chromosome transmission fidelity factor 8. (121 aa)    
Predicted Functional Partners:
DSCC1
DNA replication and sister chromatid cohesion 1.
   
 0.992
RFC5
Replication factor C subunit 5.
   
 0.989
CHTF18
Chromosome transmission fidelity factor 18.
   
 0.988
ENSPPAP00000004355
Uncharacterized protein.
   
   0.974
RFC4
Replication factor C subunit 4.
   
 0.972
RFC3
Replication factor C subunit 3.
   
 0.964
RFC2
Replication factor C subunit 2.
   
 0.958
SMC3
Structural maintenance of chromosomes protein.
   
 
 0.826
WDHD1
WD repeat and HMG-box DNA binding protein 1.
   
 
 0.826
TIMELESS
Timeless circadian regulator.
    
 
 0.821
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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