STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100980541Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (507 aa)    
Predicted Functional Partners:
LEF1
Lymphoid enhancer binding factor 1.
    
 0.832
TCF7L2
Transcription factor 7 like 2.
    
 0.793
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
    
0.766
TCF7L1
Transcription factor 7 like 1.
    
 0.734
CTNNB1
Catenin beta 1.
    
 0.732
TCF7
HMG box domain-containing protein.
    
 0.706
MAP3K20
Mitogen-activated protein kinase kinase kinase 20.
    
 0.700
JUP
Junction plakoglobin.
    
 0.675
UCK2
Uridine-cytidine kinase 2.
    
 0.599
UCKL1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
    
 0.599
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.