Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDXPUncharacterized protein. (79 aa)    
Predicted Functional Partners:
PLPBP
Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.634
ATAT1
Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...]
   
  
 0.628
NOL12
Uncharacterized protein.
      
 0.625
CFL1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 
 0.622
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 
 0.599
PDXK
Pyridoxal kinase.
     
 0.561
SH3BP1
Uncharacterized protein.
   
  
 0.561
ENSPPAP00000038954
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 
 0.547
POLDIP3
DNA polymerase delta interacting protein 3.
   
  
 0.526
PSME3
Proteasome activator subunit 3.
   
  
 0.491
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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