STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAS2R60Taste receptor type 2 member 60; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). (318 aa)    
Predicted Functional Partners:
TAS1R2
Taste 1 receptor member 2.
     
 0.800
PKD1L3
Polycystin 1 like 3, transient receptor potential channel interacting.
      
 0.723
OR2M4
Olfactory receptor.
      
 0.700
TAS1R1
Taste 1 receptor member 1.
     
 0.652
TAS1R3
Taste 1 receptor member 3.
     
 0.615
PKD2L1
Polycystin 2 like 1, transient receptor potential cation channel.
      
 0.608
CASR
Calcium sensing receptor.
     
 0.580
GPRC6A
G protein-coupled receptor class C group 6 member A.
     
 0.564
HCN4
Hyperpolarization activated cyclic nucleotide gated potassium channel 4.
      
 0.542
TAS2R50
Taste receptor type 2 member 50; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
  
  
0.523
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.