Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
GPR12G protein-coupled receptor 12; Belongs to the G-protein coupled receptor 1 family. (334 aa)    
Predicted Functional Partners:
GNB1
G protein subunit beta 1.
    
  0.744
LRRC61
Leucine rich repeat containing 61.
      
 0.624
GNG7
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.601
GNG2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.566
TAC1
Tachykinin precursor 1.
   
 
 0.540
GNB2
G protein subunit beta 2.
    
  0.520
GNB4
G protein subunit beta 4.
    
  0.520
CLVS2
Clavesin 2.
   
  
 0.501
TRPA1
Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 0.500
TMEM130
Transmembrane protein 130.
   
  
 0.498
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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