STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP12Matrix metallopeptidase 12. (470 aa)    
Predicted Functional Partners:
TIMP1
TIMP metallopeptidase inhibitor 1.
   
 0.812
TIMP2
TIMP metallopeptidase inhibitor 2.
   
 0.758
ENSPPAP00000037905
Uncharacterized protein.
   
 
 0.756
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.689
COL12A1
Collagen type XII alpha 1 chain.
   
 0.656
CTSS
Cathepsin S; Belongs to the peptidase C1 family.
   
 
 0.652
TIMP4
TIMP metallopeptidase inhibitor 4.
    
 0.640
MMP7
Matrix metallopeptidase 7.
  
0.637
SPP1
Secreted phosphoprotein 1.
   
 
 0.608
LOC100970329
Peptidase S1 domain-containing protein.
   
 0.605
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.