Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
USP12Ubiquitin specific peptidase 12; Belongs to the peptidase C19 family. (372 aa)    
Predicted Functional Partners:
USP46
Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family.
   
 
 0.992
WDR48
WD repeat domain 48.
    
 0.987
WDR20
WD repeat domain 20.
   
 0.980
DMWD
DM1 locus, WD repeat containing.
   
 0.939
AR
Androgen receptor.
    
 0.887
PHLPP1
Uncharacterized protein.
    
 
 0.856
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2.
    
 
 0.835
KXD1
Ubiquitin-like domain-containing protein.
    
 0.812
RAD51AP1
RAD51 associated protein 1.
   
 
 0.800
TSPYL6
TSPY like 6; Belongs to the nucleosome assembly protein (NAP) family.
   
   0.761
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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