Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)    
Predicted Functional Partners:
CFL1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
   0.986
ENSPPAP00000038954
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
   0.947
ACTG1
Actin gamma 1.
   
 
 0.935
ENSPPAP00000017839
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
   0.909
ENSPPAP00000031319
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
   0.885
LIMK1
LIM domain kinase 1.
   
 0.850
ENSPPAP00000024326
Uncharacterized protein.
   
 
 0.814
ACTB
Actin beta; Belongs to the actin family.
   
 
 0.814
ENSPPAP00000012927
Uncharacterized protein; Belongs to the actin family.
   
 
 0.805
PFN3
Profilin; Belongs to the profilin family.
   
 0.801
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.