node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACAT1 | ACAT2 | ENSPPAP00000023875 | ENSPPAP00000042145 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.916 |
ACAT1 | BDH1 | ENSPPAP00000023875 | ENSPPAP00000020349 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.478 |
ACAT1 | EHHADH | ENSPPAP00000023875 | ENSPPAP00000037205 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.968 |
ACAT1 | HADH | ENSPPAP00000023875 | ENSPPAP00000022134 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Uncharacterized protein. | 0.984 |
ACAT1 | HMGCL | ENSPPAP00000023875 | ENSPPAP00000024111 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.955 |
ACAT1 | HMGCLL1 | ENSPPAP00000023875 | ENSPPAP00000016455 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.940 |
ACAT1 | HMGCS2 | ENSPPAP00000023875 | ENSPPAP00000020317 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.993 |
ACAT1 | LOC100994494 | ENSPPAP00000023875 | ENSPPAP00000001793 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.968 |
ACAT1 | OXCT1 | ENSPPAP00000023875 | ENSPPAP00000000304 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.971 |
ACAT2 | ACAT1 | ENSPPAP00000042145 | ENSPPAP00000023875 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.916 |
ACAT2 | EHHADH | ENSPPAP00000042145 | ENSPPAP00000037205 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.969 |
ACAT2 | HADH | ENSPPAP00000042145 | ENSPPAP00000022134 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Uncharacterized protein. | 0.984 |
ACAT2 | HMGCL | ENSPPAP00000042145 | ENSPPAP00000024111 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.935 |
ACAT2 | HMGCLL1 | ENSPPAP00000042145 | ENSPPAP00000016455 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1. | 0.935 |
ACAT2 | HMGCS2 | ENSPPAP00000042145 | ENSPPAP00000020317 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.989 |
ACAT2 | LOC100994494 | ENSPPAP00000042145 | ENSPPAP00000001793 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.954 |
ACAT2 | OXCT1 | ENSPPAP00000042145 | ENSPPAP00000000304 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.953 |
BDH1 | ACAT1 | ENSPPAP00000020349 | ENSPPAP00000023875 | 3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. | 0.478 |
BDH1 | BDH2 | ENSPPAP00000020349 | ENSPPAP00000032941 | 3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 3-hydroxybutyrate dehydrogenase 2. | 0.960 |
BDH1 | HMGCL | ENSPPAP00000020349 | ENSPPAP00000024111 | 3-hydroxybutyrate dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.959 |