STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PSTPIP1Proline-serine-threonine phosphatase interacting protein 1. (404 aa)    
Predicted Functional Partners:
MEFV
MEFV innate immuity regulator, pyrin.
   
 0.996
ITSN2
Intersectin 2.
   
0.965
PTPN12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
   
 
 0.943
PTPN22
Protein tyrosine phosphatase non-receptor type 22.
   
 
 0.923
WAS
WASP actin nucleation promoting factor.
   
 0.916
ITSN1
Intersectin 1.
   
0.882
CD2
CD2 molecule.
   
 
 0.780
PTPN18
Protein tyrosine phosphatase non-receptor type 18.
   
 
 0.760
WASL
WASP like actin nucleation promoting factor.
   
 0.746
PTS
6-pyruvoyl tetrahydrobiopterin synthase.
      
 0.691
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.