Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSTPIP1Proline-serine-threonine phosphatase interacting protein 1. (404 aa)    
Predicted Functional Partners:
MEFV
MEFV innate immuity regulator, pyrin.
   
 0.992
PTPN12
Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades.
   
 
 0.944
ITSN2
Intersectin 2.
   
 0.920
WAS
WASP actin nucleation promoting factor.
   
 0.877
PTPN22
Protein tyrosine phosphatase non-receptor type 22.
   
 
 0.863
ITSN1
Intersectin 1.
   
 0.851
PTPN18
Protein tyrosine phosphatase non-receptor type 18.
   
 
 0.840
FASLG
Fas ligand; Belongs to the tumor necrosis factor family.
    
 
 0.730
WASL
WASP like actin nucleation promoting factor.
   
 0.730
CD2
CD2 molecule.
   
 0.700
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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