STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXL5F-box and leucine rich repeat protein 5. (684 aa)    
Predicted Functional Partners:
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
    
 0.998
IREB2
Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.
    
 0.995
LOC106635345
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.982
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.958
ENSPPAP00000039346
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.958
ACO1
Aconitase 1; Belongs to the aconitase/IPM isomerase family.
    
 0.923
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component.
    
 
 0.839
FTL
Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
      
 0.807
CIAO2B
Cytosolic iron-sulfur assembly component 2B.
    
 
 0.804
RBX1
Ring-box 1.
    
 0.775
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.