STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FKBP4Peptidylprolyl isomerase. (456 aa)    
Predicted Functional Partners:
FKBP5
Peptidylprolyl isomerase.
  
  
0.959
HSP90AA1
HATPase_c domain-containing protein.
   
 0.926
PGR
Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
   
 0.881
NR3C1
Nuclear receptor subfamily 3 group C member 1.
   
 0.864
MTOR
Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.
    
 
 0.859
HSP90AB1
HATPase_c domain-containing protein.
   
 0.823
PTGES3
Prostaglandin E synthase 3.
   
 0.803
LOC100992102
CS domain-containing protein.
   
 0.803
NR3C2
Nuclear receptor subfamily 3 group C member 2.
   
 0.776
ENSPPAP00000005988
Uncharacterized protein.
   
 0.752
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: medium (42%) [HD]