Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTGR1Prostaglandin reductase 1. (329 aa)    
Predicted Functional Partners:
HPGD
15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.939
LTA4H
Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.
   
 
 0.929
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
  
0.920
PTGR2
Uncharacterized protein.
  
  
 
0.907
CYP4F2
Cytochrome P450 family 4 subfamily F member 2; Belongs to the cytochrome P450 family.
   
 
 0.904
CYP4F3
Cytochrome P450 family 4 subfamily F member 3; Belongs to the cytochrome P450 family.
   
 
 0.904
CRYZ
Crystallin zeta.
  
 
 0.486
CAT
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
  
  
 0.404
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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