Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PSME2Proteasome activator subunit 2. (239 aa)    
Predicted Functional Partners:
PSME1
Proteasome activator subunit 1.
  
0.999
PSME3
Proteasome activator subunit 3.
  
 
0.972
PSMB9
Proteasome subunit beta.
   
 0.947
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
   
 
 0.939
PSMB4
Proteasome subunit beta; Belongs to the peptidase T1B family.
   
 0.925
TNF
Tumor necrosis factor; Belongs to the tumor necrosis factor family.
     
 0.901
PSMB7
Proteasome subunit beta.
   
 0.901
PSMB5
Proteasome subunit beta.
   
 0.898
PSMA5
Proteasome subunit alpha type.
   
 0.889
PSMB8
Proteasome subunit beta.
   
 0.888
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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