Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100972005Uncharacterized protein. (198 aa)    
Predicted Functional Partners:
IFNAR1
Interferon alpha and beta receptor subunit 1.
    
 0.969
IFNAR2
Uncharacterized protein.
    
 0.902
IRF7
Interferon regulatory factor 7.
    
 0.852
IRF3
Interferon regulatory factor 3.
    
 0.825
TYK2
Tyrosine-protein kinase.
    
 0.825
JAK1
Tyrosine-protein kinase.
    
 0.814
ISG15
ISG15 ubiquitin like modifier.
    
 0.814
IFNA6
Interferon alpha 6.
   
  0.796
IFNGR1
Interferon gamma receptor 1.
  
  
 0.792
JAK2
Tyrosine-protein kinase.
    
 0.780
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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