fit to screen
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IRX4Iroquois homeobox 4. (544 aa)    
Predicted Functional Partners:
IRX1
Iroquois homeobox 1.
   
 
 0.729
NPPA
Natriuretic peptide A.
      
 0.670
KCNJ3
Uncharacterized protein.
      
 0.652
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.631
GJA5
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.621
MKX
Mohawk homeobox.
    
 
 0.594
VSNL1
Visinin like 1.
      
 0.535
ACTN1
Actinin alpha 1.
      
 0.534
CACNA1B
Uncharacterized protein.
      
 0.530
SLC2A10
Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
      
 0.518
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (16%) [HD]