STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRX4Iroquois homeobox 4. (544 aa)    
Predicted Functional Partners:
ACTN1
Actinin alpha 1.
      
 0.648
NKX2-5
NK2 homeobox 5.
   
 
 0.604
HAND2
Uncharacterized protein.
    
 
 0.568
AKAP11
A-kinase anchoring protein 11.
      
 0.554
SLC2A10
Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.549
JUP
Junction plakoglobin.
    
 
 0.543
AGK
Acylglycerol kinase.
   
  
 0.537
LTBP2
Latent transforming growth factor beta binding protein 2.
   
 
 0.522
CACNA1B
Uncharacterized protein.
     
 0.511
SNTA1
Syntrophin alpha 1.
      
 0.507
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.