Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)    
Predicted Functional Partners:
MACROD2
Mono-ADP ribosylhydrolase 2.
      
 0.870
USH2A
Usherin.
      
 0.782
AACS
Acetoacetyl-CoA synthetase.
   
  
 0.539
ENSPPAP00000030731
Uncharacterized protein.
   
  
 0.539
PIBF1
Progesterone immunomodulatory binding factor 1.
      
 0.530
SMLR1
Small leucine rich protein 1.
      
 0.490
KIAA0825
Uncharacterized protein.
      
 0.489
CCDC6
Coiled-coil domain containing 6.
      
 0.488
ENSPPAP00000015724
Uncharacterized protein.
      
 0.486
FAM83B
Family with sequence similarity 83 member B.
      
 0.484
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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