STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MIB1Mindbomb E3 ubiquitin protein ligase 1. (929 aa)    
Predicted Functional Partners:
ZMYM4
Zinc finger MYM-type containing 4.
   
  0.798
PCM1
Pericentriolar material 1.
    
 0.740
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
 0.636
BRD2
Bromodomain containing 2.
    
 
 0.572
PCNT
Pericentrin.
    
  0.570
ZNF609
Zinc finger protein 609.
      
 0.558
DAPK1
Death associated protein kinase 1.
   
0.557
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
   
 
 0.537
SHPRH
SNF2 histone linker PHD RING helicase.
   
 0.533
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
 0.481
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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