STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)    
Predicted Functional Partners:
SERPINE1
Serpin family E member 1; Belongs to the serpin family.
   
 0.999
SERPINB2
Serpin family B member 2; Belongs to the serpin family.
    
 0.971
PLG
Plasminogen; Belongs to the peptidase S1 family.
  
  
0.966
PLAUR
Plasminogen activator, urokinase receptor.
   
 0.946
S100A10
S100 calcium binding protein A10; Belongs to the S-100 family.
   
 0.906
ENSPPAP00000001730
Ig-like domain-containing protein.
    
  0.890
SERPINF2
Serpin family F member 2; Belongs to the serpin family.
   
 0.887
ENSPPAP00000010626
Ig-like domain-containing protein.
    
  0.886
F3
Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
   
 0.851
LRP1
LDL receptor related protein 1.
    
 
 0.843
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.