HECTD3 protein (Pan paniscus) - STRING interaction network

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Score

HECTD3

HECT domain E3 ubiquitin protein ligase 3. (829 aa)

Predicted Functional Partners:

TRIP12

0.754

KXD1

0.642

PGM2

0.612

ENSPPAP00000019306

0.569

FAU

0.569

TRRAP

0.520

PGM2L1

0.517

ATG7

0.496

UBD

0.453

ZFAND4

0.449

Your Current Organism:

Pan paniscus

NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG7	ENSPPAP00000019306	ENSPPAP00000035158	ENSPPAP00000019306	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.500
ATG7	FAU	ENSPPAP00000035158	ENSPPAP00000034983	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.500
ATG7	HECTD3	ENSPPAP00000035158	ENSPPAP00000003628	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	HECT domain E3 ubiquitin protein ligase 3.	0.496
ATG7	KXD1	ENSPPAP00000035158	ENSPPAP00000040077	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin-like domain-containing protein.	0.788
ATG7	TRIP12	ENSPPAP00000035158	ENSPPAP00000040222	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Thyroid hormone receptor interactor 12.	0.858
ATG7	UBD	ENSPPAP00000035158	ENSPPAP00000001185	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin D.	0.493
ATG7	ZFAND4	ENSPPAP00000035158	ENSPPAP00000041219	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Zinc finger AN1-type containing 4.	0.519
ENSPPAP00000019306	ATG7	ENSPPAP00000019306	ENSPPAP00000035158	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.500
ENSPPAP00000019306	FAU	ENSPPAP00000019306	ENSPPAP00000034983	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.891
ENSPPAP00000019306	HECTD3	ENSPPAP00000019306	ENSPPAP00000003628	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	HECT domain E3 ubiquitin protein ligase 3.	0.569
ENSPPAP00000019306	KXD1	ENSPPAP00000019306	ENSPPAP00000040077	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-like domain-containing protein.	0.996
ENSPPAP00000019306	TRIP12	ENSPPAP00000019306	ENSPPAP00000040222	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Thyroid hormone receptor interactor 12.	0.813
ENSPPAP00000019306	TRRAP	ENSPPAP00000019306	ENSPPAP00000027205	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	0.456
ENSPPAP00000019306	UBD	ENSPPAP00000019306	ENSPPAP00000001185	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin D.	0.631
ENSPPAP00000019306	ZFAND4	ENSPPAP00000019306	ENSPPAP00000041219	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Zinc finger AN1-type containing 4.	0.790
FAU	ATG7	ENSPPAP00000034983	ENSPPAP00000035158	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.500
FAU	ENSPPAP00000019306	ENSPPAP00000034983	ENSPPAP00000019306	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.891
FAU	HECTD3	ENSPPAP00000034983	ENSPPAP00000003628	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	HECT domain E3 ubiquitin protein ligase 3.	0.569
FAU	KXD1	ENSPPAP00000034983	ENSPPAP00000040077	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Ubiquitin-like domain-containing protein.	0.996
FAU	TRIP12	ENSPPAP00000034983	ENSPPAP00000040222	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	Thyroid hormone receptor interactor 12.	0.813