Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ROBO4Roundabout guidance receptor 4. (1007 aa)    
Predicted Functional Partners:
DIPK2B
Divergent protein kinase domain 2B.
   
  
 0.978
SLIT2
Slit guidance ligand 2.
   
 0.974
SLIT3
Slit guidance ligand 3.
   
 0.965
SLIT1
Slit guidance ligand 1.
   
 0.930
ROBO1
Roundabout guidance receptor 1.
    
 
 0.739
ENSPPAP00000010920
LRRCT domain-containing protein.
   
 0.730
CLDN5
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.692
MMRN2
Multimerin 2.
   
 0.683
NRP1
Neuropilin; Belongs to the neuropilin family.
   
 
 0.654
GDNF
Glial cell derived neurotrophic factor.
     
 0.622
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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