STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (343 aa)    
Predicted Functional Partners:
SPINT1
Serine peptidase inhibitor, Kunitz type 1.
   
 0.848
SPINT2
Serine peptidase inhibitor, Kunitz type 2.
   
 0.732
DSP
Desmoplakin.
    
 
 0.616
TJP3
Tight junction protein 3; Belongs to the MAGUK family.
   
  
 0.613
IRF6
Interferon regulatory factor 6.
   
 
 0.572
TMEM63A
Transmembrane protein 63A.
   
  
 0.555
FURIN
Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.
  
 
 0.545
ZNF157
Zinc finger protein 157.
    
 
 0.542
SCNN1A
Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
   
  
 0.529
MET
MET proto-oncogene, receptor tyrosine kinase.
    
 0.521
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.