Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GGA1Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (639 aa)    
Predicted Functional Partners:
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
  
0.982
GGA3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3.
   
 
0.978
RABEP1
Rabaptin, RAB GTPase binding effector protein 1.
    
 0.964
IGF2R
Insulin like growth factor 2 receptor.
    
 
 0.954
BACE1
Beta-secretase 1; Belongs to the peptidase A1 family.
    
 0.949
SORT1
Sortilin.
    
 
 0.916
RABGEF1
RAB guanine nucleotide exchange factor 1.
   
 0.899
ARF3
ADP ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.870
ARF1
ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.869
SORL1
Sortilin related receptor 1.
    
 
 0.842
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.