STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF6Uncharacterized protein. (1609 aa)    
Predicted Functional Partners:
RAP1B
RAP1B, member of RAS oncogene family.
   
 0.950
RAP1A
RAP1A, member of RAS oncogene family.
   
 0.950
MAGI2
Membrane associated guanylate kinase, WW and PDZ domain containing 2.
    
 0.928
MAGI1
Uncharacterized protein.
    
 0.924
F11R
F11 receptor.
     
 0.909
PTPN13
Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.
    
 
 0.906
RAPGEF2
Rap guanine nucleotide exchange factor 2.
  
  
 
0.901
ENSPPAP00000006260
Uncharacterized protein.
   
 0.524
ENSPPAP00000035001
Uncharacterized protein.
   
 0.524
DIRAS1
DIRAS family GTPase 1.
   
 0.449
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.