STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NETO1Neuropilin and tolloid like 1. (533 aa)    
Predicted Functional Partners:
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
   
 
 0.768
GRIK1
Glutamate ionotropic receptor kainate type subunit 1.
   
 
 0.694
GRIK4
Glutamate ionotropic receptor kainate type subunit 4.
   
 
 0.597
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
   
 
 0.549
GRIK5
Glutamate ionotropic receptor kainate type subunit 5.
   
 
 0.549
GRIK3
Glutamate ionotropic receptor kainate type subunit 3.
   
 
 0.543
KARS1
Lysine--tRNA ligase.
      
 0.503
C1S
Complement C1s; Belongs to the peptidase S1 family.
   
  
 0.445
SEMA3E
Semaphorin 3E; Belongs to the semaphorin family.
      
 0.433
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
  
 0.415
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.