STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKK1Ankyrin repeat and kinase domain containing 1. (689 aa)    
Predicted Functional Partners:
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
    
 0.739
TTC12
Tetratricopeptide repeat domain 12.
 
  
 0.702
COMT
Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.
      
 0.672
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
   
0.587
INPP1
Inositol polyphosphate-1-phosphatase.
     
 0.578
SLC25A12
Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.567
AVPR1B
Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
   
 0.566
SLC6A4
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.563
CTNNA3
Catenin alpha 3.
    
 0.562
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
  
 0.560
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.