Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP36Rho GTPase activating protein 36. (535 aa)    
Predicted Functional Partners:
ASPM
Abnormal spindle microtubule assembly.
   
 
 0.657
TTK
TTK protein kinase.
   
    0.628
RAB12
RAB12, member RAS oncogene family.
     
 0.624
NDC80
NDC80 kinetochore complex component.
   
    0.598
CEP55
Centrosomal protein 55.
   
    0.591
ESPL1
Extra spindle pole bodies like 1, separase.
   
  
 0.577
IQCA1L
IQ motif containing with AAA domain 1 like.
   
 
 0.575
RHOB
Ras homolog family member B.
    
 0.569
RHOA
Uncharacterized protein.
    
 0.569
RHOC
Ras homolog family member C.
    
 0.569
Your Current Organism:
Pan paniscus
NCBI taxonomy Id: 9597
Other names: P. paniscus, bonobo, pygmy chimpanzee
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